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北海道大学 大学院地球環境科学研究院 環境生物科学部門 生態遺伝学分野 早川研究室 (Hayakawa Lab, Faculty of Environmental Earth Science, Hokkaido University)

野生動物 x 行動 x 生態 x 進化 x ゲノム


野生動物の行動・生態・進化をゲノム解析で研究しています

研究論文 PublicationsNEWS&FAQ

2024年
2023年
  • The admixed brushtail possum genome reveals invasion history in New Zealand and novel imprinted genes
    『ブラシテイルポッサム（フクロギツネ）におけるゲノムの混合はニュージーランドへの移入の歴史と新奇のインプリンティング遺伝子を明らかにする』
    https://doi.org/10.1038/s41467-023-41784-8
  • Diet-related factors strongly shaped the gut microbiota of Japanese macaques
    『ニホンザルの腸内マイクロバイオームは採食品目と強い関連がある』
    https://doi.org/10.1002/ajp.23555
  • Eighty million years of rapid evolution of the primate Y chromosome
    『8000万年にわたる霊長類Y染色体の急速な進化』
    https://doi.org/10.1038/s41559-022-01974-x
  • Phylogenomic analyses provide insights into primate evolution
    『霊長類の進化の理解に向けた系統ゲノミクス解析』
    https://doi.org/10.1126/science.abn6919
  • Cervicovaginal microbiome in patients with recurrent pregnancy loss
    『不育症患者における頸膣マイクロバイオーム』
    https://doi.org/10.1016/j.jri.2023.103944
2022年
  • Seasonal responses and host uniqueness of gut microbiome of Japanese macaques in lowland Yakushima
    『屋久島低地部のニホンザルの腸内マイクロバイオームの季節応答と宿主固有性』
    https://doi.org/10.1186/s42523-022-00205-9
  • Dietary niche breadth influences the effects of urbanization on the gut microbiota of sympatric rodents
    『同所的に生息する齧歯類の腸内マイクロバイオータにおける都市化効果は採食ニッチの広がりに影響される』
    https://doi.org/10.1002/ece3.9216
  • Functional Diversity and Evolution of Bitter Taste Receptors in Egg-Laying Mammals
    『卵を産む哺乳類における苦味受容体の機能多様性と進化』
    https://doi.org/10.1093/molbev/msac107 [日本語プレスリリース]
  • Genome assembly of the numbat (Myrmecobius fasciatus), the only termitivorous marsupial
    『唯一のシロアリ食有袋類であるナンバット（フクロアリクイ）（Myrmecobius fasciatus）のゲノムアセンブリ』
    https://doi.org/10.46471/gigabyte.47
  • Initiation of the Primate Genome Project
    『霊長類ゲノムプロジェクトの始動』
    https://doi.org/10.24272/j.issn.2095-8137.2022.001
2021年
2020年
2019年
  • Gut microbiota composition of Japanese macaques associates with extent of human encroachment
    『ニホンザルの腸内細菌叢組成は人間の介入の程度に関連している』
    https://doi.org/10.1002/ajp.23072
  • Host selection of hematophagous leeches (Haemadipsa japonica): Implications for iDNA studies
    『吸血ヒル（ヤマビル：Haemadipsa japonica）の宿主選択：iDNA研究に向けて』
    https://doi.org/10.1111/1440-1703.12059 [日本語解説]
  • A natural point mutation in the bitter taste receptor TAS2R16 causes inverse agonism of arbutin in lemur gustation
    『キツネザルの味覚において、苦味受容体TAS2R16の突然変異がアルブチンの苦味抑制を引き起こした』
    https://doi.org/10.1098/rspb.2019.0884 [日本語プレスリリース]
2018年
2017年
2016年
2015年
2014年
  • Frequent expansions of the bitter taste receptor gene repertoire during evolution of mammals in the Euarchontoglires clade
    『哺乳類進化の真主齧類クレードにおける苦味受容体遺伝子レパートリーの頻繁な拡大』
    https://doi.org/10.1093/molbev/msu144 [日本語要旨]
2013年
2012年
  • Eco-geographical diversification of bitter taste receptor genes (TAS2Rs) among subspecies of chimpanzees (Pan troglodytes)
    『チンパンジー（Pan troglodytes）亜種間における苦味受容体遺伝子（TAS2R）の多様化の生態地理』
    https://doi.org/10.1371/journal.pone.0043277 [日本語プレスリリース]
  • A novel composite retrotransposon derived from or generated independently of the SVA (SINE/VNTR/Alu) transposon has undergone proliferation in gibbon genomes
    『SVA（SINE/VNTR/Alu）トランスポゾンから派生した、あるいは独立に生じた新規の複合型レトロトランスポゾンがテナガザルゲノムで拡散してる』
    https://doi.org/10.1266/ggs.87.181
2011年

一覧 Style: NLM

原著論文
  1. Katsushima H, Kashiwagi N, Hamano T, Kogi K, Sato R, Nakata K, Nishino M, Hayakawa T. Fat taste receptors and fatty milk in dolphins. Marine Mammal Science. e13195. doi: 10.1111/mms.13195. Epub ahead of print.

  2. Takada H, Sato A, Katsuta S, Nakamura K, Ohwaki A, Kane Y, Hayakawa T, Inoue E. Dietary partitioning in two gleaning bats, Japanese long-eared bats (Plecotus sacrimontis) and Ussuri tube-nosed bats (Murina ussuriensis): consuming insects of same order but different developmental stages. Anim. Biol. doi: 10.1163/15707563-bja10139. Epub ahead of print.

  3. Yoshimura H, Hayakawa T, Kikuchi DM, Zhumabai UK, Qi H, Sugimoto T, Sharma K, Kinoshita K. Metabarcoding analysis provides insight into the link between prey and plant intake in a large alpine cat carnivore, the snow leopard. R. Soc. Open Sci. 2024;11240132. doi: 10.1098/rsos.240132.

  4. Kondo K, Suzuki M, Amadaira M, Araki C, Watanabe R, Murakami K, Ochiai S, Ogura T, Hayakawa T. Association of maternal genetics with the gut microbiome and eucalypt diet selection in captive koalas. PeerJ. 2024;12:e17385. doi: 10.7717/peerj.17385.

  5. Hou M, Akhtar MS, Hayashi M, Ashino R, Matsumoto-Oda A, Hayakawa T, Ishida T, Melin AD, Imai H, Kawamura S. Reduction of bitter taste receptor gene family in folivorous colobine primates relative to omnivorous cercopithecine primates. Primates. 2024 Apr 11. doi: 10.1007/s10329-024-01124-w. Epub ahead of print. PMID: 38605281.

  6. Takeuchi H, Matsuishi TF, Hayakawa T. A tradeoff evolution between acoustic fat bodies and skull muscles in toothed whales. Gene. 2024 Jan 13;901:148167. doi: 10.1016/j.gene.2024.148167. Epub ahead of print. PMID: 38224921.

  7. Sakamoto S, Matsushita Y, Itoigawa A, Ezawa T, Fujitani T, Takakura K, Zhou Y, Zhang G, Grutzner F, Kawamura S, Hayakawa T. Color vision evolution in egg-laying mammals: insights from visual photoreceptors and daily activities of Australian echidnas. Zoological Lett. 2024 Jan 2;10(1):2. doi: 10.1186/s40851-023-00224-7. PMID: 38167154; PMCID: PMC10759620.

  8. Bond DM, Ortega-Recalde O, Laird MK, Hayakawa T, Richardson KS, Reese FCB, Kyle B, McIsaac-Williams BE, Robertson BC, van Heezik Y, Adams AL, Chang WS, Haase B, Mountcastle J, Driller M, Collins J, Howe K, Go Y, Thibaud-Nissen F, Lister NC, Waters PD, Fedrigo O, Jarvis ED, Gemmell NJ, Alexander A, Hore TA. The admixed brushtail possum genome reveals invasion history in New Zealand and novel imprinted genes. Nat Commun. 2023 Oct 17;14(1):6364. doi: 10.1038/s41467-023-41784-8. PMID: 37848431; PMCID: PMC10582058.

  9. Lee W, Hayakawa T, Kiyono M, Yamabata N, Enari H, Enari HS, Fujita S, Kawazoe T, Asai T, Oi T, Kondo T, Uno T, Seki K, Shimada M, Tsuji Y, Langgeng A, MacIntosh A, Suzuki K, Yamada K, Onishi K, Ueno M, Kubo K, Hanya G. Diet-related factors strongly shaped the gut microbiota of Japanese macaques. Am J Primatol. 2023 Dec;85(12):e23555. doi: 10.1002/ajp.23555. Epub 2023 Sep 28. PMID: 37766673.

  10. Zhou Y, Zhan X, Jin J, Zhou L, Bergman J, Li X, Rousselle MMC, Belles MR, Zhao L, Fang M, Chen J, Fang Q, Kuderna L, Marques-Bonet T, Kitayama H, Hayakawa T, Yao YG, Yang H, Cooper DN, Qi X, Wu DD, Schierup MH, Zhang G. Eighty million years of rapid evolution of the primate Y chromosome. Nat Ecol Evol. 2023 Jul;7(7):1114-1130. doi: 10.1038/s41559-022-01974-x. Epub 2023 Jun 2. PMID: 37268856.

  11. Shao Y, Zhou L, Li F, Zhao L, Zhang BL, Shao F, Chen JW, Chen CY, Bi X, Zhuang XL, Zhu HL, Hu J, Sun Z, Li X, Wang D, Rivas-González I, Wang S, Wang YM, Chen W, Li G, Lu HM, Liu Y, Kuderna LFK, Farh KK, Fan PF, Yu L, Li M, Liu ZJ, Tiley GP, Yoder AD, Roos C, Hayakawa T, Marques-Bonet T, Rogers J, Stenson PD, Cooper DN, Schierup MH, Yao YG, Zhang YP, Wang W, Qi XG, Zhang G, Wu DD. Phylogenomic analyses provide insights into primate evolution. Science. 2023 Jun 2;380(6648):913-924. doi: 10.1126/science.abn6919. Epub 2023 Jun 1. PMID: 37262173.

  12. Mori R, Hayakawa T, Hirayama M, Ozawa F, Yoshihara H, Goto S, Kitaori T, Ozaki Y, Sugiura-Ogasawara M. Cervicovaginal microbiome in patients with recurrent pregnancy loss. J Reprod Immunol. 2023 Jun;157:103944. doi: 10.1016/j.jri.2023.103944. Epub 2023 Apr 7. PMID: 37060795.

  13. Sawada A, Hayakawa T, Kurihara Y, Lee W, Hanya G. Seasonal responses and host uniqueness of gut microbiome of Japanese macaques in lowland Yakushima. Anim Microbiome. 2022 Sep 27;4(1):54. doi: 10.1186/s42523-022-00205-9. PMID: 36163043; PMCID: PMC9513907.

  14. Anders JL, Mychajliw AM, Moustafa MAM, Mohamed WMA, Hayakawa T, Nakao R, Koizumi I. Dietary niche breadth influences the effects of urbanization on the gut microbiota of sympatric rodents. Ecol Evol. 2022 Sep 9;12(9):e9216. doi: 10.1002/ece3.9216. PMID: 36177145; PMCID: PMC9463044.

  15. Itoigawa A, Hayakawa T, Zhou Y, Manning AD, Zhang G, Grutzner F, Imai H. Functional Diversity and Evolution of Bitter Taste Receptors in Egg-Laying Mammals. Mol Biol Evol. 2022 Jun 2;39(6):msac107. doi: 10.1093/molbev/msac107. PMID: 35652727; PMCID: PMC9161717.

  16. Peel E, Silver L, Brandies P, Hayakawa T, Belov K, Hogg CJ. Genome assembly of the numbat (Myrmecobius fasciatus), the only termitivorous marsupial. Gigabyte. 2022; 1. doi: 10.46471/gigabyte.47.

  17. Anders JL, Moustafa MAM, Mohamed WMA, Hayakawa T, Nakao R, Koizumi I. Comparing the gut microbiome along the gastrointestinal tract of three sympatric species of wild rodents. Sci Rep. 2021 Oct 7;11(1):19929. doi: 10.1038/s41598-021-99379-6. PMID: 34620922; PMCID: PMC8497572.

  18. Toda Y, Hayakawa T, Itoigawa A, Kurihara Y, Nakagita T, Hayashi M, Ashino R, Melin AD, Ishimaru Y, Kawamura S, Imai H, Misaka T. Evolution of the primate glutamate taste sensor from a nucleotide sensor. Curr Biol. 2021 Oct 25;31(20):4641-4649.e5. doi: 10.1016/j.cub.2021.08.002. Epub 2021 Aug 26. Erratum in: Curr Biol. 2021 Oct 25;31(20):4675-4676. PMID: 34450087.

  19. Toda Y, Ko MC, Liang Q, Miller ET, Rico-Guevara A, Nakagita T, Sakakibara A, Uemura K, Sackton T, Hayakawa T, Sin SYW, Ishimaru Y, Misaka T, Oteiza P, Crall J, Edwards SV, Buttemer W, Matsumura S, Baldwin MW. Early origin of sweet perception in the songbird radiation. Science. 2021 Jul 9;373(6551):226-231. doi: 10.1126/science.abf6505. PMID: 34244416.

  20. Ito T, Hayakawa T, Suzuki–Hashido N, Hamada Y, Kurihara Y, Hanya G, Kaneko A, Natsume T, Aisu S, Honda T, Yachimori S, Anezaki T, Omi T, Hayama S, Tanaka M, Wakamori H, Imai H, Kawamoto Y. Phylogeographic history of Japanese macaques. J Biogeogr. 2021 Jun;48(6):1420-1431. doi: 10.1111/jbi.14087. Epub 2021 Apr 15.

  21. Lee W, Hayakawa T, Kurihara Y, Hanzawa M, Sawada A, Kaneko A, Morimitsu Y, Natsume T, Aisu S, Ito T, Honda T, Hanya G. Stomach and colonic microbiome of wild Japanese macaques. Am J Primatol. 2021 May;83(5):e23242. doi: 10.1002/ajp.23242. Epub 2021 Feb 10. PMID: 33566369.

  22. Kinoshita K, Indo Y, Tajima T, Kuze N, Miyakawa E, Kobayashi T, Nakamura T, Ogata M, Okumura F, Hayakawa T, Morimura N, Mori Y, Okamoto M, Ozaki Y, Hirata S. Comparative analysis of sperm motility in liquid and seminal coagulum portions between Bornean orangutan (Pongo pygmaeus) and chimpanzee (Pan troglodytes). Primates. 2021 May;62(3):467-473. doi: 10.1007/s10329-020-00887-2. Epub 2021 Jan 19. Erratum in: Primates. 2021 Apr 20;: PMID: 33462771.

  23. Suzuki-Hashido N, Tsuchida S, Hayakawa T, Sakamoto M, Azumano A, Seino S, Matsuda I, Ohkuma M, Ushida K. Lactobacillus nasalidis sp. nov., isolated from the forestomach of a captive proboscis monkey (Nasalis larvatus). Int J Syst Evol Microbiol. 2021 Apr;71(4). doi: 10.1099/ijsem.0.004787. PMID: 33906706.

  24. Itoigawa A, Fierro F, Chaney ME, Lauterbur ME, Hayakawa T, Tosi AJ, Niv MY, Imai H. Lowered sensitivity of bitter taste receptors to β-glucosides in bamboo lemurs: an instance of parallel and adaptive functional decline in TAS2R16? Proc Biol Sci. 2021 Apr 14;288(1948):20210346. doi: 10.1098/rspb.2021.0346. Epub 2021 Apr 14. PMID: 33849315; PMCID: PMC8059561.

  25. Zhou Y, Shearwin-Whyatt L, Li J, Song Z, Hayakawa T, Stevens D, Fenelon JC, Peel E, Cheng Y, Pajpach F, Bradley N, Suzuki H, Nikaido M, Damas J, Daish T, Perry T, Zhu Z, Geng Y, Rhie A, Sims Y, Wood J, Haase B, Mountcastle J, Fedrigo O, Li Q, Yang H, Wang J, Johnston SD, Phillippy AM, Howe K, Jarvis ED, Ryder OA, Kaessmann H, Donnelly P, Korlach J, Lewin HA, Graves J, Belov K, Renfree MB, Grutzner F, Zhou Q, Zhang G. Platypus and echidna genomes reveal mammalian biology and evolution. Nature. 2021 Apr;592(7856):756-762. doi: 10.1038/s41586-020-03039-0. Epub 2021 Jan 6. PMID: 33408411; PMCID: PMC8081666.

  26. Matsumoto T, Hanamura S, Kooriyama T, Hayakawa T, Inoue E. Female chimpanzees giving first birth in their natal group in Mahale: attention to incest between brothers and sisters. Primates. 2021 Mar;62(2):279-287. doi: 10.1007/s10329-020-00886-3. Epub 2021 Jan 14. PMID: 33442833.

  27. Hanya G, Tackmann J, Sawada A, Lee W, Pokharel SS, de Castro Maciel VG, Toge A, Kuroki K, Otsuka R, Mabuchi R, Liu J, Hatakeyama M, Yamasaki E, von Mering C, Shimizu-Inatsugi R, Hayakawa T, Shimizu KK, Ushida K. Fermentation Ability of Gut Microbiota of Wild Japanese Macaques in the Highland and Lowland Yakushima: In Vitro Fermentation Assay and Genetic Analyses. Microb Ecol. 2020 Aug;80(2):459-474. doi: 10.1007/s00248-020-01515-8. Epub 2020 Apr 24. PMID: 32328670.

  28. Shirasu M, Ito S, Itoigawa A, Hayakawa T, Kinoshita K, Munechika I, Imai H, Touhara K. Key Male Glandular Odorants Attracting Female Ring-Tailed Lemurs. Curr Biol. 2020 Jun 8;30(11):2131-2138.e4. doi: 10.1016/j.cub.2020.03.037. Epub 2020 Apr 16. PMID: 32302584.

  29. Purba LHPS, Widayati KA, Suzuki-Hashido N, Itoigawa A, Hayakawa T, Nila S, Juliandi B, Suryobroto B, Imai H. Evolution of the bitter taste receptor TAS2R38 in colobines. Primates. 2020 May;61(3):485-494. doi: 10.1007/s10329-020-00799-1. Epub 2020 Feb 1. PMID: 32006126.

  30. Lee W, Hayakawa T, Kiyono M, Yamabata N, Hanya G. Gut microbiota composition of Japanese macaques associates with extent of human encroachment. Am J Primatol. 2019 Dec;81(12):e23072. doi: 10.1002/ajp.23072. Epub 2019 Dec 1. PMID: 31788810.

  31. Hanya G, Morishima K, Koide T, Otani Y, Hongo S, Honda T, Okamura H, Higo Y, Hattori M, Kondo Y, Kurihara Y, Jin S, Otake A, Shiroisihi I, Takakuwa T, Yamamoto H, Suzuki H, Kajimura H, Hayakawa T, Suzuki-Hashido N, Nakano T. Host selection of hematophagous leeches (Haemadipsa japonica): Implications for iDNA studies. Ecol Res. 2019 Nov;34(6):842-855. doi: 10.1111/1440-1703.12059.

  32. Itoigawa A, Hayakawa T, Suzuki-Hashido N, Imai H. A natural point mutation in the bitter taste receptor TAS2R16 causes inverse agonism of arbutin in lemur gustation. Proc Biol Sci. 2019 Jun 12;286(1904):20190884. doi: 10.1098/rspb.2019.0884. Epub 2019 Jun 5. PMID: 31161904; PMCID: PMC6571456.

  33. Hayakawa T, Nathan SKSS, Stark DJ, Saldivar DAR, Sipangkui R, Goossens B, Tuuga A, Clauss M, Sawada A, Fukuda S, Imai H, Matsuda I. First report of foregut microbial community in proboscis monkeys: are diverse forests a reservoir for diverse microbiomes? Environ Microbiol Rep. 2018 Dec;10(6):655-662. doi: 10.1111/1758-2229.12677. Epub 2018 Sep 27. PMID: 29992728.

  34. Nishi E, Suzuki-Hashido N, Hayakawa T, Tsuji Y, Suryobroto B, Imai H. Functional decline of sweet taste sensitivity of colobine monkeys. Primates. 2018 Nov;59(6):523-530. doi: 10.1007/s10329-018-0679-2. Epub 2018 Sep 6. PMID: 30191350.

  35. Hayakawa T, Sawada A, Tanabe AS, Fukuda S, Kishida T, Kurihara Y, Matsushima K, Liu J, Akomo-Okoue EF, Gravena W, Kashima M, Suzuki M, Kadowaki K, Suzumura T, Inoue E, Sugiura H, Hanya G, Agata K. Improving the standards for gut microbiome analysis of fecal samples: insights from the field biology of Japanese macaques on Yakushima Island. Primates. 2018 Sep;59(5):423-436. doi: 10.1007/s10329-018-0671-x. Epub 2018 Jun 25. PMID: 29942984.

  36. Johnson RN, O'Meally D, Chen Z, Etherington GJ, Ho SYW, Nash WJ, Grueber CE, Cheng Y, Whittington CM, Dennison S, Peel E, Haerty W, O'Neill RJ, Colgan D, Russell TL, Alquezar-Planas DE, Attenbrow V, Bragg JG, Brandies PA, Chong AY, Deakin JE, Di Palma F, Duda Z, Eldridge MDB, Ewart KM, Hogg CJ, Frankham GJ, Georges A, Gillett AK, Govendir M, Greenwood AD, Hayakawa T, Helgen KM, Hobbs M, Holleley CE, Heider TN, Jones EA, King A, Madden D, Graves JAM, Morris KM, Neaves LE, Patel HR, Polkinghorne A, Renfree MB, Robin C, Salinas R, Tsangaras K, Waters PD, Waters SA, Wright B, Wilkins MR, Timms P, Belov K. Adaptation and conservation insights from the koala genome. Nat Genet. 2018 Aug;50(8):1102-1111. doi: 10.1038/s41588-018-0153-5. Epub 2018 Jul 2. PMID: 29967444; PMCID: PMC6197426.

  37. Moriya-Ito K, Hayakawa T, Suzuki H, Hagino-Yamagishi K, Nikaido M. Evolution of vomeronasal receptor 1 (V1R) genes in the common marmoset (Callithrix jacchus). Gene. 2018 Feb 5;642:343-353. doi: 10.1016/j.gene.2017.11.048. Epub 2017 Nov 17. PMID: 29155331.

  38. Hanya G, Naito S, Namioka E, Ueda Y, Sato Y, Pastrana JA, He T, Yan X, Saito M, Costa RFP, Allanic M, Honda T, Kurihara Y, Yumoto T, Hayakawa T. Morphometric and genetic determination of age class and sex for fecal pellets of sika deer (Cervus nippon). Mammal Study. 2017 Dec 18;42(4):1-8. doi: 10.3106/041.042.0406.

  39. Tatsumoto S, Go Y, Fukuta K, Noguchi H, Hayakawa T, Tomonaga M, Hirai H, Matsuzawa T, Agata K, Fujiyama A. Direct estimation of de novo mutation rates in a chimpanzee parent-offspring trio by ultra-deep whole genome sequencing. Sci Rep. 2017 Nov 1;7(1):13561. doi: 10.1038/s41598-017-13919-7. PMID: 29093469; PMCID: PMC5666008.

  40. Purba LH, Widayati KA, Tsutsui K, Suzuki-Hashido N, Hayakawa T, Nila S, Suryobroto B, Imai H. Functional characterization of the TAS2R38 bitter taste receptor for phenylthiocarbamide in colobine monkeys. Biol Lett. 2017 Jan;13(1):20160834. doi: 10.1098/rsbl.2016.0834. PMID: 28123110; PMCID: PMC5310586.

  41. Tsutsui K, Otoh M, Sakurai K, Suzuki-Hashido N, Hayakawa T, Misaka T, Ishimaru Y, Aureli F, Melin AD, Kawamura S, Imai H. Variation in ligand responses of the bitter taste receptors TAS2R1 and TAS2R4 among New World monkeys. BMC Evol Biol. 2016 Oct 12;16(1):208. doi: 10.1186/s12862-016-0783-0. PMID: 27733116; PMCID: PMC5062938.

  42. Carelli FN, Hayakawa T, Go Y, Imai H, Warnefors M, Kaessmann H. The life history of retrocopies illuminates the evolution of new mammalian genes. Genome Res. 2016 Mar;26(3):301-14. doi: 10.1101/gr.198473.115. Epub 2016 Jan 4. PMID: 26728716; PMCID: PMC4772013.

  43. Toju H, Yamamoto S, Tanabe AS, Hayakawa T, Ishii HS. Network modules and hubs in plant-root fungal biomes. J R Soc Interface. 2016 Mar;13(116):20151097. doi: 10.1098/rsif.2015.1097. PMID: 26962029; PMCID: PMC4843674.

  44. Suzuki-Hashido N, Hayakawa T, Matsui A, Go Y, Ishimaru Y, Misaka T, Abe K, Hirai H, Satta Y, Imai H. Rapid Expansion of Phenylthiocarbamide Non-Tasters among Japanese Macaques. PLoS One. 2015 Jul 22;10(7):e0132016. doi: 10.1371/journal.pone.0132016. PMID: 26201026; PMCID: PMC4511751.

  45. Kishida T, Thewissen J, Hayakawa T, Imai H, Agata K. Aquatic adaptation and the evolution of smell and taste in whales. Zoological Lett. 2015 Feb 13;1:9. doi: 10.1186/s40851-014-0002-z. PMID: 26605054; PMCID: PMC4604112.

  46. Hayakawa T, Suzuki-Hashido N, Matsui A, Go Y. Frequent expansions of the bitter taste receptor gene repertoire during evolution of mammals in the Euarchontoglires clade. Mol Biol Evol. 2014 Aug;31(8):2018-31. doi: 10.1093/molbev/msu144. Epub 2014 Apr 23. PMID: 24758778.

  47. Toda Y, Nakagita T, Hayakawa T, Okada S, Narukawa M, Imai H, Ishimaru Y, Misaka T. Two distinct determinants of ligand specificity in T1R1/T1R3 (the umami taste receptor). J Biol Chem. 2013 Dec 27;288(52):36863-77. doi: 10.1074/jbc.M113.494443. Epub 2013 Nov 8. PMID: 24214976; PMCID: PMC3873546.

  48. Hayakawa T, Sugawara T, Go Y, Udono T, Hirai H, Imai H. Eco-geographical diversification of bitter taste receptor genes (TAS2Rs) among subspecies of chimpanzees (Pan troglodytes). PLoS One. 2012;7(8):e43277. doi: 10.1371/journal.pone.0043277. Epub 2012 Aug 16. PMID: 22916235; PMCID: PMC3420883.

  49. Hara T, Hirai Y, Baicharoen S, Hayakawa T, Hirai H, Koga A. A novel composite retrotransposon derived from or generated independently of the SVA (SINE/VNTR/Alu) transposon has undergone proliferation in gibbon genomes. Genes Genet Syst. 2012;87(3):181-90. doi: 10.1266/ggs.87.181. Erratum in: Genes Genet Syst. 2014;89(3):149. PMID: 22976393.

  50. Hayakawa T, Nakashima M, Nakamura M. Immigration of a large number of adolescent female chimpanzees into the Mahale M group. Pan Afr News. 2011 Jun;18(1):8-10. doi: 10.5134/143527.

総説
  1. Wu DD, Qi XG, Yu L, Li M, Liu ZJ, Yoder AD, Roos C, Hayakawa T, Rogers J, Marques-Bonet T, Su B, Yao YG, Zhang YP, Zhang G. Initiation of the Primate Genome Project. Zool Res. 2022 Mar 18;43(2):147-149. doi: 10.24272/j.issn.2095-8137.2022.001. PMID: 35008130; PMCID: PMC8920853.

  2. Hayakawa T. Taste of chimpanzee foods. In Nakamura M, Hosaka K, Itoh N, Zamma K (Eds.), Mahale Chimpanzees: 50 Years of Research (Cambridge University Press). 2015 Sep;246-258. doi: 10.1017/CBO9781107280533.

問い合わせ先（研究室代表者）

〒060-0810
北海道札幌市北区北10西5
北海道大学 環境科学院
早川卓志

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