{"id":275,"date":"2019-07-29T17:19:00","date_gmt":"2019-07-29T08:19:00","guid":{"rendered":"https:\/\/noah.ees.hokudai.ac.jp\/yoshida\/?p=275"},"modified":"2019-07-29T17:30:31","modified_gmt":"2019-07-29T08:30:31","slug":"%e5%a4%9a%e4%be%a1%e4%b8%8d%e9%a3%bd%e5%92%8c%e8%84%82%e8%82%aa%e9%85%b8%e5%90%88%e6%88%90%e9%85%b5%e7%b4%a0%e3%81%8c%e7%82%ad%e7%b4%a0%e9%8e%96%e3%81%ae%e9%95%b7%e3%81%95%e3%82%92%e6%b1%ba%e3%82%81","status":"publish","type":"post","link":"https:\/\/noah.ees.hokudai.ac.jp\/yoshida\/?p=275","title":{"rendered":"\u591a\u4fa1\u4e0d\u98fd\u548c\u8102\u80aa\u9178\u5408\u6210\u9175\u7d20\u304c\u70ad\u7d20\u9396\u306e\u9577\u3055\u3092\u6c7a\u3081\u308b\u3057\u304f\u307f"},"content":{"rendered":"

\u591a\u4fa1\u4e0d\u98fd\u548c\u8102\u80aa\u9178\u306e\u5408\u6210\u9175\u7d20\u306b\u95a2\u3057\u3066\u3001\u5408\u6210\u3055\u308c\u308b\u8102\u80aa\u9178\u306e\u70ad\u7d20\u9396\u306e\u9577\u3055\u304c\u3069\u306e\u3088\u3046\u306b\u8abf\u7bc0\u3055\u308c\u3066\u3044\u308b\u304b\u306b\u3064\u3044\u3066\u306e\u3001\u5317\u5927\u5de5\u5b66\u90e8\u3068\u798f\u4e95\u770c\u7acb\u5927\u3001\u305d\u3057\u3066\u5354\u548c\u767a\u9175\u306e\u30b0\u30eb\u30fc\u30d7\u306b\u3088\u308b\u7814\u7a76\u3067\u3059\u3002<\/p>\n

Hayashi, Shohei, Mai Naka, Kenshin Ikeuchi, Makoto Ohtsuka, Kota Kobayashi, Yasuharu Satoh, Yasushi Ogasawara, et al.<\/p>\n

\u201cControl Mechanism for Carbon-Chain Length in Polyunsaturated Fatty-Acid Synthases.\u201d<\/p>\n

Angewandte Chemie International Edition 58, no. 20 (2019): 6605\u201310. https:\/\/doi.org\/10.1002\/anie.201900771<\/a>.<\/p>\n

\u30d0\u30af\u30c6\u30ea\u30a2\u306e\u591a\u4fa1\u4e0d\u98fd\u548c\u8102\u80aa\u9178(PUFA)\u5408\u6210\u9175\u7d20\u306f\u8907\u6570\u306e\u30dd\u30ea\u30da\u30d7\u30c1\u30c9\u304b\u3089\u6210\u308b\u8907\u5408\u4f53\u3067\u3001\u305d\u308c\u305e\u308c\u306e\u30dd\u30ea\u30da\u30d7\u30c1\u30c9\u3092\u30b3\u30fc\u30c9\u3059\u308b\u907a\u4f1d\u5b50\u306f\u30b2\u30ce\u30e0\u4e0a\u306e\u3072\u3068\u3064\u3068\u3053\u308d\u306b\u304b\u305f\u307e\u3063\u3066\u5b58\u5728 \u3057\u3066\u3044\u308b\u3002EPA(\u70ad\u7d20\u9396\u306e\u9577\u3055\u306f20)\u5408\u6210\u9175\u7d20\u907a\u4f1d\u5b50\u3082DHA(\u70ad\u7d20\u9396\u306e\u9577\u3055\u306f22)\u5408\u6210\u9175\u7d20\u907a\u4f1d\u5b50\u3082A, B, C, D\u306e4\u3064\u306e\u907a\u4f1d\u5b50\u3067\u69cb\u6210\u3055\u308c\u3066\u3044\u3066\u3001\u305d\u308c\u305e\u308c\u306e\u907a\u4f1d\u5b50\u306b\u306f\u305d\u306e\u914d\u5217\u304b\u3089\u4e88\u60f3\u3055\u308c\u308b\u6a5f\u80fd\u9818\u57df(\u30c9\u30e1\u30a4\u30f3)\u304c\u306a\u3089\u3093\u3067\u3044\u308b\u3002\u4e21\u8005\u306e\u9175\u7d20\u907a\u4f1d\u5b50\u306e\u30c9\u30e1\u30a4\u30f3\u69cb\u9020\u306f\u3068\u3066\u3082\u3088\u304f\u4f3c\u3066\u3044\u308b\u305f\u3081\u3001EPA\u3092\u4f5c\u308b\u304bDHA\u3092\u4f5c\u308b\u304b\u3092\u3069\u306e\u30c9\u30e1\u30a4\u30f3\u304c\u6c7a\u3081\u3066\u3044\u308b\u304b\u306f\u308f\u304b\u3063\u3066\u3044\u306a\u3044\u3002\u305d\u3053\u3067\u3001\u8457\u8005\u3089\u306e\u30b0\u30eb\u30fc\u30d7\u306f\u3001\u907a\u4f1d\u5b50\u3092\u53d6\u308a\u66ff\u3048\u305f\u308a\u3001\u7d99\u304e\u63a5\u304e\u3057\u305f\u308a\u3057\u3066\u3001\u907a\u4f1d\u5b50\u306e\u3069\u306e\u90e8\u5206\u304cPUFA\u306e\u9577\u3055\u3092\u6c7a\u3081\u3066\u3044\u308b\u304b\u8abf\u3079\u305f\u3002<\/p>\n

\u307e\u305a\u3001\u907a\u4f1d\u5b50\u306e\u3046\u3061\u3001\u3069\u306e\u907a\u4f1d\u5b50\u304c\u9577\u3055\u306b\u95a2\u308f\u3063\u3066\u3044\u308b\u304b\u8abf\u3079\u308b\u305f\u3081\u306b\u3001EPA\u5408\u6210\u907a\u4f1d\u5b50\u3068DHA\u5408\u6210\u907a\u4f1d\u5b50\u3092\u53d6\u308a\u66ff\u3048\u308b\u5b9f\u9a13\u3092\u884c\u306a\u3063\u305f\u3002EPA\u5408\u6210\u907a\u4f1d\u5b50\u306eC\u907a\u4f1d\u5b50\u3068DHA\u5408\u6210\u907a\u4f1d\u5b50\u306eA, B, D\u907a\u4f1d\u5b50\u3092\u7d44\u307f\u5408\u308f\u305b\u308b\u3068DHA\u3067\u306f\u306a\u304f\u3001EPA\u304c\u5408\u6210\u3055\u308c\u305f\u3002\u9006\u306b\u3001DHA\u5408\u6210\u907a\u4f1d\u5b50\u306eC\u907a\u4f1d\u5b50\u3068EPA\u5408\u6210\u907a\u4f1d\u5b50\u306eA, B, D\u907a\u4f1d\u5b50\u3092\u7d44\u307f\u5408\u308f\u305b\u308b\u3068EPA\u3067\u306f\u306a\u304f\u3001DHA\u304c\u5408\u6210\u3055\u308c\u305f\u3002\u3053\u306e\u7d50\u679c\u306f\u3001C\u907a\u4f1d\u5b50\u304c\u7523\u7269\u306e\u9577\u3055\u3092\u6c7a\u3081\u3066\u3044\u308b\u3001\u3068\u3044\u3046\u3053\u3068\u3092\u793a\u3057\u3066\u3044\u308b\u3002<\/p>\n

\u6b21\u306b\u3001C\u907a\u4f1d\u5b50\u306b\u3042\u308b\u3069\u306e\u30c9\u30e1\u30a4\u30f3\u304c\u6c7a\u3081\u3066\u3044\u308b\u306e\u304b\u3092\u8abf\u3079\u308b\u305f\u3081\u306b\u3001C\u907a\u4f1d\u5b50\u3092\u524d\u534a\u3068\u5f8c\u534a\u306b\u5206\u3051\u3001\u7570\u306a\u308b\u3082\u306e\u3069\u3046\u3057\u3092\u7d44\u307f\u5408\u308f\u305b\u3066\u307f\u305f\u3068\u3053\u308d\u3001\u907a\u4f1d\u5b50\u306e\u524d\u534a\u90e8\u5206(KSC<\/sub> \u30c9\u30e1\u30a4\u30f3)\u306b\u3088\u3063\u3066\u6c7a\u307e\u3063\u3066\u3044\u308b\u3053\u3068\u304c\u308f\u304b\u3063\u305f\u3002<\/p>\n

\u3055\u3089\u306b\u3001\u3053\u306e\u30c9\u30e1\u30a4\u30f3\u304c\u3069\u306e\u3088\u3046\u306a\u53cd\u5fdc\u3092\u89e6\u5a92\u3059\u308b\u304b\u3092\u69d8\u3005\u306a\u53cd\u5fdc\u57fa\u8cea\u3068\u306e\u7d44\u307f\u5408\u308f\u305b\u3067\u8abf\u3079\u3066\u307f\u308b\u3068\u3001DHA\u5408\u6210\u9175\u7d20\u306e KSC<\/sub> \u30c9\u30e1\u30a4\u30f3\u304c\u70ad\u7d20\u939620\u304b\u3089\u70ad\u7d20\u939622\u3078\u306e\u4f38\u9577\u53cd\u5fdc\u3092\u89e6\u5a92\u3059\u308b\u3053\u3068\u304c\u308f\u304b\u3063\u305f\u3002\u3057\u305f\u304c\u3063\u3066\u3001KSC<\/sub>\u30c9\u30e1\u30a4\u30f3\u304c\u7523\u7269\u306e\u70ad\u7d20\u9396\u306e\u9577\u3055\u3092\u6c7a\u3081\u3066\u3044\u308b\u3068\u8003\u3048\u3089\u308c\u308b\u3002<\/p>\n

\u8457\u8005\u3089\u306f\u3001\u3053\u306e\u77e5\u898b\u306b\u57fa\u3065\u304d\u3001\u771f\u6838\u751f\u7269\u3067\u3042\u308b\u5fae\u7d30\u85fb\u985e\u3001 Aurantiochytrium<\/i> sp. OH4 \u7531\u6765\u306eDHA\u5408\u6210\u9175\u7d20\u907a\u4f1d\u5b50\u306eKSC<\/sub>\u30c9\u30e1\u30a4\u30f3\u306b\u7a81\u7136\u5909\u7570\u3092\u5c0e\u5165\u3057\u3001DHA\u306b\u52a0\u3048EPA\u3082\u5408\u6210\u3059\u308b\u907a\u4f1d\u5b50\u3092\u5f97\u308b\u3053\u3068\u306b\u3082\u6210\u529f\u3057\u3066\u3044\u308b\u3002<\/p>\n

\u73fe\u5728\u3001\u5fae\u7d30\u85fb\u985e\u306e\u5927\u91cf\u57f9\u990a\u306b\u3088\u3063\u3066DHA\u306e\u5546\u696d\u751f\u7523\u304c\u53ef\u80fd\u306b\u306a\u3063\u3066\u3044\u308b\u3002\u4e00\u65b9\u3001EPA\u3092\u7523\u751f\u3059\u308b\u5fae\u751f\u7269\u306f\u3044\u304f\u3064\u304b\u77e5\u3089\u308c\u3066\u306f\u3044\u308b\u304c\u3001\u3044\u305a\u308c\u3082\u5927\u91cf\u57f9\u990a\u306b\u9069\u3057\u3066\u3044\u308b\u3068\u306f\u3044\u3048\u306a\u3044\u3002\u3057\u304b\u3057\u306a\u304c\u3089\u3001\u3053\u306e\u7814\u7a76\u306b\u3088\u3046\u306b\u3001PUFA\u5408\u6210\u9175\u7d20\u306e\u89e6\u5a92\u53cd\u5fdc\u6a5f\u5e8f\u3092\u660e\u3089\u304b\u306b\u3057\u3066\u3044\u3051\u3070\u3001DHA\u7523\u751f\u5fae\u7d30\u85fb\u985e\u304b\u3089EPA\u7523\u751f\u682a\u3092\u4f5c\u308a\u51fa\u3059\u3053\u3068\u3082\u53ef\u80fd\u3068\u306a\u308b\u3060\u308d\u3046\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"

\u591a\u4fa1\u4e0d\u98fd\u548c\u8102\u80aa\u9178\u306e\u5408\u6210\u9175\u7d20\u306b\u95a2\u3057\u3066\u3001\u5408\u6210\u3055\u308c\u308b\u8102\u80aa\u9178\u306e\u70ad\u7d20\u9396\u306e\u9577\u3055\u304c\u3069\u306e\u3088\u3046\u306b\u8abf\u7bc0\u3055\u308c\u3066\u3044\u308b\u304b\u306b\u3064\u3044\u3066\u306e\u3001\u5317\u5927\u5de5\u5b66\u90e8\u3068\u798f\u4e95\u770c\u7acb\u5927\u3001\u305d\u3057\u3066\u5354\u548c\u767a\u9175\u306e\u30b0\u30eb\u30fc\u30d7\u306b\u3088\u308b\u7814\u7a76\u3067\u3059\u3002 Hayashi, Shohei, Mai Nak … “\u591a\u4fa1\u4e0d\u98fd\u548c\u8102\u80aa\u9178\u5408\u6210\u9175\u7d20\u304c\u70ad\u7d20\u9396\u306e\u9577\u3055\u3092\u6c7a\u3081\u308b\u3057\u304f\u307f” \u306e<\/span>\u7d9a\u304d\u3092\u8aad\u3080<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_jetpack_memberships_contains_paid_content":false,"footnotes":""},"categories":[2],"tags":[13],"class_list":["post-275","post","type-post","status-publish","format-standard","hentry","category-diary","tag-review"],"jetpack_featured_media_url":"","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/noah.ees.hokudai.ac.jp\/yoshida\/index.php?rest_route=\/wp\/v2\/posts\/275"}],"collection":[{"href":"https:\/\/noah.ees.hokudai.ac.jp\/yoshida\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/noah.ees.hokudai.ac.jp\/yoshida\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/noah.ees.hokudai.ac.jp\/yoshida\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/noah.ees.hokudai.ac.jp\/yoshida\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=275"}],"version-history":[{"count":7,"href":"https:\/\/noah.ees.hokudai.ac.jp\/yoshida\/index.php?rest_route=\/wp\/v2\/posts\/275\/revisions"}],"predecessor-version":[{"id":282,"href":"https:\/\/noah.ees.hokudai.ac.jp\/yoshida\/index.php?rest_route=\/wp\/v2\/posts\/275\/revisions\/282"}],"wp:attachment":[{"href":"https:\/\/noah.ees.hokudai.ac.jp\/yoshida\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=275"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/noah.ees.hokudai.ac.jp\/yoshida\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=275"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/noah.ees.hokudai.ac.jp\/yoshida\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=275"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}